Property photo 1
Property photo 2
Property photo 3
Property photo 4
Property photo 5

$1,950,000

110 E Greenville Street, Anderson SC, 29621

Price per sqftN/A
Property typeCommercial

Overview

Active

Listed Jun 11, 2026

Updated 4 weeks ago

Endless investment potential on one of Anderson's most iconic corners! Nestled in one of Anderson’s most prominent and well-trafficked locations, this multi-building, multi-tenant portfolio property offers an unparalleled opportunity for business owners and investors alike. Occupying nearly half of one of the city’s most iconic blocks, this property is a cornerstone of Anderson’s bustling commercial hub. Its strategic location at the intersection of E Greenville Street and Main Street ensures maximum visibility and accessibility, making it an ideal destination for retail, professional services, or dining establishments. Spanning 1.21 acres with over 14,000 square feet of versatile space, the property features multiple buildings designed to accommodate a range of commercial needs. Positioned at the corner of E Calhoun and McDuffie Streets, the site also enjoys frontage along E Greenville Street, with red-light access on three sides to ensure seamless traffic flow for patrons and clients. The property’s layout offers flexibility, allowing tenants to customize the spaces to suit their specific requirements, whether they are a retail vendor, restaurateur, or professional office provider. The visibility and accessibility of this property are unmatched. Its location within the heart of Anderson places it amidst thriving businesses, providing a steady stream of potential customers. The property’s position on key city streets ensures consistent exposure to both pedestrian and vehicle traffic, making it a highly desirable site for a range of ventures. Whether you’re looking to establish a flagship retail store, expand a professional office portfolio, or create a dining destination in one of South Carolina’s fastest-growing cities, this property offers the space, location, and flexibility needed to bring your vision to life. With its prime location and multi-tenant potential, this commercial listing is a rare opportunity to secure a presence in the heart of Anderson’s vibrant economic landscape. Don’t miss your chance to be part of this thriving community.

Additional information

MLS® ID
1594425

Interior Features

Cooling
Yes
Heating
Yes
Basement
No

Exterior Features

Lot Size
1.21 Acres

Other Property Details

Taxes
$17,722
Tax Frequency
Annually

Also listed on AAR

Listed by Sherry L Traynum, Howard Hanna Allen Tate/Pine to Palm Realty, 864-376-6336 

Listing data is derived in whole or in part from the Greater Greenville Association of REALTORS® and is for consumers' personal, noncommercial use only. Greater Greenville Association of REALTORS®. All Rights Reserved. All information deemed reliable but not guaranteed and should be independently verified. All properties are subject to prior sale, change, or withdrawal. Neither listing broker(s) nor Francine Powers shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless.

©2026 Greater Greenville Association of REALTORS®. All rights reserved. 

Data last updated 3:42 AM UTC, 8/12/2026

Powered by Luxury Presence